منابع مشابه
Biomimetic biphasic scaffolds for osteochondral defect repair
The osteochondral defects caused by vigorous trauma or physical disease are difficult to be managed. Tissue engineering provides a possible option to regenerate the damaged osteochondral tissues. For osteochondral reconstruction, one intact scaffold should be considered to support the regeneration of both cartilage and subchondral bone. Therefore, the biphasic scaffolds with the mimic structure...
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Operations for the relief of symptoms in spondylolisthesis range from simple excision of the loose lamina and spinous process to fusion of three vertebrae from behind or two by the anterior route. Each method has its advocates but a review of techniques by Henderson (1966) concluded that only 65 to 70 per cent of operations gave satisfactory results. An extensive search of the literature has fa...
متن کاملAdvanced Strategies for Articular Cartilage Defect Repair
Articular cartilage is a unique tissue owing to its ability to withstand repetitive compressive stress throughout an individual's lifetime. However, its major limitation is the inability to heal even the most minor injuries. There still remains an inherent lack of strategies that stimulate hyaline-like articular cartilage growth with appropriate functional properties. Recent scientific advances...
متن کاملPorous tantalum biocomposites for osteochondral defect repair
OBJECTIVES We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would allow for secure implant fixation, subsequent integration and remodeling. MATERIALS AND METHODS Adult sheep were randomly assigned to one of three groups (n = 8/group): 1. trabecular metal...
متن کاملInjectable gel graft for bone defect repair.
AIM To examine the performance of an injectable gel graft made of transglutaminase (Tg)-crosslinked gelatin gel with BMP-2 (BMP-2-Tg-Gel) for bone defect repair in animal models. MATERIALS & METHODS BMP-2 mixed with gelatin gel was crosslinked using Tg. The release of tethered BMP-2 through autocrine and paracrine pathways was demonstrated by using C2C12 and NIH 3T3 cells, respectively. BMP-2...
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ژورنال
عنوان ژورنال: Nature Reviews Materials
سال: 2019
ISSN: 2058-8437
DOI: 10.1038/s41578-019-0092-5